IMSF team members

contact information

• e-mail address: alexander.fluegel(at)med.uni-goettingen.de

secretariat

• telephone: +49 551 3961158
• fax: +49 551 3961145
• e-mail address: imsf(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961158
• e-mail address: cludwig(at)gwdg.de

secretariat

• telephone: +49 551 3961158
• fax: +49 551 3961145
• e-mail address: imsf(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961139
• e-mail address: francesca.odoardi(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961141
• e-mail address: dmitri.lodygin(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961140
• e-mail address: fred.luehder(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961143
• e-mail address: alyssa.baert(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961217
• e-mail address: michael.bartl(at)med.uni-goettingen.de

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• My research interest is the investigation and characterization of neuroinflammatory, cellular processes in the prodromal and early stages of Parkinson’s disease. This includes the analysis of peripheral blood mononuclear cells (PBMCs) with regard to specific T-cell activation on the protein α-synuclein. One focus is the examination of blood samples from patients at risk for or with established Parkinson’s disease or dementia with Lewy bodies. My main aim is to establish biomarkers that enable early diagnosis, are predictive of disease progression and correlate with established clinical scales. A further aim is to describe new pathways that are associated with the disease process and may represent potential therapeutic approaches.

contact information

• telephone: +49 551 3961144
• e-mail address: roger.cugota-canals(at)med.uni-goettingen.de

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• The results of our research group point indicate that the lung plays a major role in the autoimmunity occurring in the central nervous system. Antigen-specific T cells can be reactivated in the lung and then undergo a complex molecular reprogramming. Thereby these cells gain a migratory phenotype that permits them to enter the CNS (Odoardi et al., 2012). The lung differs from all other organs with regard to its milieu conditions. In my project, I’m investigating how the lung environment influences the activation of immune cells, and by extension the occurrence of autoimmunity in the CNS.

contact information

• telephone: +49 551 396144
• e-mail address: alex.gasconsaperas(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961144
• e-mail address: michael.haberl(at)med.uni-goettingen.de

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• My PhD project is the description and characterization of T cell and myeloid cell motility at the blood-brain barrier. My emphasis lies in combining intravital imaging with mathematical approaches to understand inflammatory processes in the CNS better. I’m interested in visualizing immunological processes with intravital microscopy and then processing the data with quantitative analyses using statistical models and algorithms from the area of machine learning, also integrating transcriptome data into these models.

contact information

• telephone: +49 551 3961142
• e-mail address: lisbeth.harder(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961144
• e-mail address: leon.hosang(at)med.uni-goettingen.de

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• Risk factors for multiple sclerosis include smoking, COPD and infections and inflammation of the airways. This points to a central role of the lung in the pathogenesis of this autoimmune disease. Our research group could show in an animal model of multiple sclerosis called experimental autoimmune encephalomyelitis (EAE) that the lung is an essential check-point for autoaggressive T cells which trigger the disease. After the cells are transferred into the animal, they surprisingly first reside in the lung tissue. During this stay the cells are reprogrammed and given the ability to overcome the blood-brain barrier and trigger the inflammation in the central nervous system typical of EAE. The aim of my project is to investigate the role of the lung and the specific characteristics of this organ in the pathogenesis of EAE.

contact information

• telephone: +49 551 3961144
• e-mail address: soghra.kargaran(at)med.uni-goettingen.de

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• Our eye is especially protected from potentially damaging influences by the immune system. Nevertheless, this protection is not absolute; inflammation can occur in the eye and is a common complication in CNS autoimmune disorders such as multiple sclerosis. How these (auto)immune reactions develop in the ocular milieu is as yet poorly understood. In my PhD project I aim to understand the dynamics of the immune processes underlying T-cell-mediated ocular inflammation. Furthermore, I will investigate the effects of T-cell-mediated inflammation on the resident cells. Technically, to address these points I will track the inflammation in vivo using advanced intravital imaging techniques (e.g. two-photon microscopy and MRI) and characterize it by cellular and molecular analyses.

contact information

• telephone: +49 551 3961142
• e-mail address: henrike.koerner(at)med.uni-goettingen.de

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• The focus of my current research is on how T cells can invade the CNS and cause inflammatory reactions there. I’m interested in how the antigen specificity of the T cells influences their invasive targeting of specific areas of the CNS (grey matter or white matter).

contact information

• telephone: +49 551 3961143
• e-mail address: a.kraeft(at)stud.uni-goettingen.de

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contact information

• telephone: +49 551 3961159
• e-mail address: marc-andre.lecuyer(at)med.uni-goettingen.de

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• Multiple Sclerosis (MS) is an inflammatory disorder of the central nervous system (CNS) characterized by multifocal lesions in the brain and spinal cord. These lesions are caused by infiltrating immune cells that take advantage of and/or actively participate in the disruption of the blood-brain barrier (BBB). Identifying novel key players involved in this process is thus an important goal of mine in the hope that it will lead to the development of MS therapies aimed at promoting BBB integrity during neuroinflammation.

contact information

• telephone: +49 551 3961143
• e-mail address: arianna.merlini(at)med.uni-goettingen.de

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• I am a neurologist and achieved my PhD in neuroimmunology in Prof. Odoardi’s research group (2021), where I am now continuing my research as a postdoc. My research focus is the characterization of T-cell-mediated immune responses in different compartments of the central nervous system, using a combination of intravital microscopy, flow cytometry and transcriptomics.

contact information

• telephone: +49 551 3961144
• e-mail address: lukas.mueller-kirschbaum(at)med.uni-goettingen.de

• Autoreactive T cells play a decisive role in the pathogenesis of multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE). The aim of my PhD project is to better understand the T-cell-driven inflammatory processes in the central nervous system. My work especially concentrates on the direct interplay between autoreactive T cells and neurons. By means of targeted genetic manipulation I want to manipulate the bond between the T cells and neurons and thereby find out more about the functional significance of their interaction.

contact information

• telephone: +49 551 3961143
• e-mail address: kira.pahl(at)stud.uni-goettingen.de

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contact information

• telephone: +49 551 3961143
• e-mail address: mandy.pavel(at)stud.uni-goettingen.de

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contact information

• telephone: +49 551 3961143
• e-mail address: r.scherer(at)stud.uni-goettingen.de

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contact information

• telephone: +49 551 3961143
• e-mail address: annalia.schicktanz(at)stud.uni-goettingen.de

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contact information

• telephone: +49 551 3961143
• e-mail address: annika.schmidke(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961122
• fax: +49 551 3913061122
• e-mail address: omar.diaz(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961125
• e-mail address: alzain.osman(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961137
• e-mail address: birgit.curdt(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961133
• e-mail address: simone.hamann(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961131
• e-mail address: leonard.linde(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961143
• e-mail address: brigitte.salzmann-aue(at)med.uni-goettingen.de

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contact information

• telephone: +49 551 3961143
• fax: +49 551 3961145
• e-mail address: martina.weig(at)med.uni-goettingen.de

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